Tuesday, September 29 · 2026 season

MLB computer picks — today's full slate

Every matchup below is graded by our model against the current market. The edge next to each pick is how many runs our projection differs from the sportsbook line — the bigger the gap, the stronger the play. 4 of 4 games cleared our edge threshold today. Click any game for the full preview.

Reading the cards: Strong plays clear our highest edge threshold; Lean plays are smaller edges worth a lighter unit; Pass means no edge worth betting. Auto-updated Tuesday, September 29, 2026 at 3:00 AM EDT.
PHIPHI
@
ATLATL
Tue, Sep 29 · 6:00 PM ET  Strong
Run linePHI +1.5 +1.2
TotalOver 6.5 +2.2
MoneylineATL -110
ProjectionPHI 4 – ATL 5
Model confidence85%
BOSBOS
@
NYYNYY
Wed, Sep 30 · 12:10 AM ET  Strong
Run lineBOS +1.5 +0.8
TotalOver 6 +3.3
MoneylineNYY -125
ProjectionBOS 4 – NYY 5
Model confidence85%
CHCCHC
@
SDSD
Wed, Sep 30 · 2:00 AM ET  Strong
Run lineCHC +1.5 +1.1
TotalOver 7.5 +0.7
MoneylineSD -115
ProjectionCHC 4 – SD 4
Model confidence74%
CWSCWS
@
HOUHOU
Tue, Sep 29 · 9:00 PM ET  Lean
Run lineHOU -1.5 +0.1
TotalOver 8 +0.4
MoneylineHOU -160
ProjectionCWS 3 – HOU 5
Model confidence59%

How to bet these picks responsibly

Size by confidence

More on strong plays, less on leans. A flat 1-unit strong / 0.5-unit lean plan keeps variance manageable.

Shop for the number

Half a point matters. Always take the best available line across your sportsbooks.

Bet edges early

When the model disagrees sharply with an opener, the market often corrects toward us. Early bettors get the best price.